Dr Sarah Teichmann

 Wellcome Trust Sanger Institute, UK

 http://www.sanger.ac.uk/science/groups/teichmann-group

Understanding Cellular Heterogeneity

From techniques such as microscopy and FACS analysis, we know that many cell populations harbour heterogeneity in morphology and protein expression. With the advent of high throughput single cell RNA-sequencing, we can now quantify transcriptomic cell-to-cell variation. I will discuss technical advances and biological insights into understanding cellular heterogeneity in T cells and ES cells using single cell RNA-sequencing.