Professor Gideon Schreiber

 Weizmann Institute of Science, Israel

 http://www.weizmann.ac.il/Biomolecular_Sciences/Schreiber/

Specific protein-protein interactions form a major part of the basic organization of living cells. My laboratory studies structure/function relations of protein-protein interactions and how these relate to biological signaling. For this purpose, we adopted a multidisciplinary approach including biophysical and biological bench work, protein- engineering, bioinformatics, and algorithm development and applied the gained knowledge towards solving biological questions.
Our research focuses on:

• Biophysical and kinetic studies of protein-protein interactions in vitro and in vivo
• The molecular architecture of protein-protein interfaces
• Development of bioinformatics tools
• Investigating the differential activities of type I interferons
• Development of transgenic mice models to investigate human interferon action